This review examines the role of thermal interoception—awareness of body temperature—in shaping physiological states and its impact on physical, emotional, and social well-being. We describe the neural pathways and mechanisms involved in thermal processing and environmental heat exchange and how thermal interoception influences both autonomic and behavioral responses, contributing to survival and homeostasis. Additionally, the review highlights the significance of thermal signals and thermoregulation in determining higher-order cognitive and emotional functions, such as regulating sleep patterns and activity levels, monitoring physical well-being, regulating emotions, and even social interactions. We describe the existing instruments for assessing body temperature and thermal awareness and call for further research to investigate the role of thermal interoception in emotional and social domains. We also discuss potential therapeutic applications, particularly in the context of psychosomatic and neurological disorders characterized by emotional dysregulation, disrupted sleep and mood patterns, social difficulties, and alterations in self-consciousness.